Publications

Neuronal blockade of thyroid hormone signaling increases sensitivity to diet-induced obesity in adult male mice: Author(s) : Rial Pensado E, Canaple L, Guyot R, Clemmensen C, Wiersema J, Wu S, Richard S, Boelen A, D Müller T, López M, Flamant F, Gauthier K,; Journal : Endocrinology; 2023
Prenatal exposure to paraquat and nanoscaled TiO2 aerosols alters the gene expression of the developing brain: Author(s) : Hamdaoui Q, Zekri Y, Richard S, Aubert D, Guyot R, Markossian S, Gauthier K, Gaie-Levrel F, Bencsik A, Flamant F,; Journal : Chemosphere; 2022
Brown adipocytes local response to thyroid hormone is required for adaptive thermogenesis in adult male mice: Author(s) : Zekri Y, Guyot R, Suñer I, Canaple L, Stein A, Petit J, Aubert D, Richard S, Flamant F, Gauthier K,; Journal : Elife; 2022
Functional definition of thyroid hormone response elements based on a synthetic STARR-seq screen: Author(s) : Flamant F, Zekri Y, Guyot R,; Journal : Endocrinology; 2022
A disease-associated mutation in thyroid hormone receptor α1 causes hearing loss and sensory hair cell patterning defects in mice: Author(s) : Affortit C, Blanc F, Nasr J, Ceccato J, Markossian S, Guyot R, Puel J, Flamant F, Wang J,; Journal : Sci Signal; 2022
An Atlas of Thyroid Hormone Receptors' Target Genes in Mouse Tissues: Author(s) : Zekri Y, Guyot R, Flamant F,; Journal : Int J Mol Sci; 2022
Assessment of pesticides capacity to act as agonists/antagonists of the thyroid hormone nuclear receptors: Author(s) : Zekri Y, Agnol L, Flamant F, Guyot R,; Journal : iScience; 2021
Central vs. Peripheral Action of Thyroid Hormone in Adaptive Thermogenesis: A Burning Topic: Author(s) : Zekri Y, Flamant F, Gauthier K,; Journal : Cells; 2021
PRMT1 Is Critical for the Transcriptional Activity and the Stability of the Progesterone Receptor.: Author(s) : Malbeteau L, Poulard C, Languilaire C, Mikaelian I, Flamant F, Le Romancer M, Corbo L,; Journal : iScience; 2020
Two novel cases of resistance to thyroid hormone due to THRA mutation (RTHα): Author(s) : Le Maire A, Bouhours-Nouet N, Soamalala J, Delphine M, Paloni M, Guee L, Heron D, Mignot C, Illouz F, Joubert F, Briet C, Rodien P, Bourguet W, Flamant F, Guyot R,; Journal : Thyroid; 2020
A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons: Author(s) : Richard S, Guyot R, Rey-Millet M, Prieux M, Markossian S, Aubert D, Flamant F,; Journal : iScience; 2020
Protocols for Studying How Thyroid Hormone Receptors Trigger Adaptive Thermogenesis in Mice.: Author(s) : Gauthier K,; Journal : Methods Mol Biol; 2018
Thyroid hormone in the regulation of hepatocellular carcinoma and its microenvironment.: Author(s) : Manka P, Coombes J, Boosman R, Gauthier K, Papa S, Syn W,; Journal : Cancer Lett; 2018
Thyroid Hormone Receptor Alpha Deletion in ApoE-/- Mice Alters the Arterial Renin-Angiotensin System and Vascular Smooth Muscular Cell Cholesterol Metabolism: Author(s) : Neggazi S, Canaple L, Hamlat N, Gauthier K, Samarut J, Bricca G, Aouichat-Bouguerra S, Beylot M,; Journal : J Vasc Res; 2018
Regulation of T3 Availability in the Developing Brain: The Mouse Genetics Contribution: Author(s) : Richard S, Flamant F,; Journal : Frontiers in Endocrinology; 2018
CRISPR/Cas9 Editing of the Mouse Thra Gene Produces Models with Variable Resistance to Thyroid Hormone: Author(s) : Markossian S,; Journal : Thyroid; 2018
Two Protocols to Study the Interactions of Thyroid Hormone Receptors with Other Proteins and Chromatin: Author(s) : Guan W, Guyot R, Flamant F,; 2018
Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing.: Author(s) : Teixeira M, Py B, Bosc C, Laubreton D, Moutin M, Marvel J, Flamant F, Markossian S,; Journal : Sci Rep; 2018
Neuronal expression of a thyroid hormone receptor alpha mutation alters mouse behaviour: Author(s) : Richard S, Aguilera N, Thevenet M, Dkhissi-Benyahya O, Flamant F,; Journal : Behav Brain Res; 2017
Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin: Author(s) : Guan W, Guyot R, Samarut J, Flamant F, Wong J, Gauthier K,; Journal : Proc Natl Acad Sci U S A; 2017
Genetic Investigation of Thyroid Hormone Receptor Function in the Developing and Adult Brain: Author(s) : Flamant F, Gauthier K, Richard S,; Journal : Curr Top Dev Biol; 2017
Thyroid hormone signaling pathways. Time for a more precise nomenclature: Author(s) : Flamant F, Cheng S, Hollenberg A, Moeller L, Samarut J, Wondisford F, Yen P, Refetoff S,; Journal : Endocrinology; 2017
Neuronal expression of a thyroid hormone receptor alpha mutation alters mouse behaviour: Author(s) : Richard S, Aguilera N, Thevenet M, Dkhissi-Benyahya O, Flamant F,; Journal : Behav Brain Res; 2016
CRISPR/Cas9: a breakthrough in generating mouse models for endocrinologists: Author(s) : Markossian S, Flamant F,; Journal : J Mol Endocrinol; 2016
Futures Challenges in Thyroid Hormone Signaling Research: Author(s) : Flamant F,; Journal : Front Endocrinol (Lausanne); 2016
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease: Author(s) : Finan B, Clemmensen C, Zhu Z, Stemmer K, Gauthier K, Muller L, De Angelis M, Moreth K, Neff F, Perez-Tilve D, Fischer K, Lutter D, Sanchez-Garrido M, Liu P, Tuckermann J, Malehmir M, Healy M, Weber A, Heikenwalder M, Jastroch M, Kleinert M, Jall S, Brandt S, Flamant F, Schramm K, Biebermann H, Doring Y, Weber C, Habegger K, Keuper M, Gelfanov V, Liu F, Kohrle J, Rozman J, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Hofmann S, Yang B, Tschop M, DiMarchi R, Muller T,; Journal : Cell; 2016
Unique features of a global human ectoparasite identified through sequencing of the bed bug genome: Author(s) : Benoit J, Adelman Z, Reinhardt K, Dolan A, Poelchau M, Jennings E, Szuter E, Hagan R, Gujar H, Shukla J, Zhu F, Mohan M, Nelson D, Rosendale A, Derst C, Resnik V, Wernig S, Menegazzi P, Wegener C, Peschel N, Hendershot J, Blenau W, Predel R, Johnston P, Ioannidis P, Waterhouse R, Nauen R, Schorn C, Ott M, Maiwald F, Johnston J, Gondhalekar A, Scharf M, Peterson B, Raje K, Hottel B, Armisen D, Crumiere A, Refki P, Santos M, Sghaier E, Viala S, Khila A, Ahn S, Childers C, Lee C, Lin H, Hughes D, Duncan E, Murali S, Qu J, Dugan S, Lee S, Chao H, Dinh H, Han Y, Doddapaneni H, Worley K, Muzny D, Wheeler D, Panfilio K, Vargas Jentzsch I, Vargo E, Booth W, Friedrich M, Weirauch M, Anderson M, Jones J, Mittapalli O, Zhao C, Zhou J, Evans J, Attardo G, Robertson H, Zdobnov E, Ribeiro J, Gibbs R, Werren J, Palli S, Schal C, Richards S,; Journal : Nat Commun; 2016
Thyroid Hormone Signaling in the Mouse Retina: Author(s) : Arbogast P, Flamant F, Godement P, Glosmann M, Peichl L,; Journal : PLoS One; 2016
TRalpha receptor mutations extend the spectrum of syndromes of reduced sensitivity to thyroid hormone: Author(s) : Vlaeminck-Guillem V, Espiard S, Flamant F, Wemeau J,; Journal : Presse Med; 2015
Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance: Author(s) : Ozmadenci D, Feraud O, Markossian S, Kress E, Ducarouge B, Gibert B, Ge J, Durand I, Gadot N, Plateroti M, Bennaceur-Griscelli A, Scoazec J, Gil J, Deng H, Bernet A, Mehlen P, Lavial F,; Journal : Nat Commun; 2015
Editorial: "Thyroid Hormone in Brain and Brain Cells": Author(s) : Flamant F, Koibuchi N, Bernal J,; Journal : Front Endocrinol (Lausanne); 2015
Human odontoblast-like cells produce nitric oxide with antibacterial activity upon TLR2 activation: Author(s) : Farges J, Bellanger A, Ducret M, Aubert-Foucher E, Richard B, Alliot-Licht B, Bleicher F, Carrouel F,; Journal : Front Physiol; 2015
A Novel Mutation in THRA Gene Associated With an Atypical Phenotype of Resistance to Thyroid Hormone: Author(s) : Espiard S, Savagner F, Flamant F, Vlaeminck-Guillem V, Guyot R, Munier M, d'Herbomez M, Bourguet W, Pinto G, Rose C, Rodien P, Wemeau J,; Journal : J Clin Endocrinol Metab; 2015
A temporary compendium of thyroid hormone target genes in brain: Author(s) : Chatonnet F, Flamant F, Morte B,; Journal : Biochim Biophys Acta; 2015
The targeted inactivation of TRbeta gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production: Author(s) : Selmi-Ruby S, Bouazza L, Obregon M, Conscience A, Flamant F, Samarut J, Borson-Chazot F, Rousset B,; Journal : Endocrinology; 2014
Deciphering direct and indirect influence of thyroid hormone with mouse genetics: Author(s) : Picou F, Fauquier T, Chatonnet F, Richard S, Flamant F,; Journal : Mol Endocrinol; 2014
Toxicogenomic analysis of the ability of brominated flame retardants TBBPA and BDE-209 to disrupt thyroid hormone signaling in neural cells: Author(s) : Guyot R, Chatonnet F, Gillet B, Hughes S, Flamant F,; Journal : Toxicology; 2014
Nongenomic, TRbeta-dependent, thyroid hormone response gets genetic support: Author(s) : Gauthier K, Flamant F,; Journal : Endocrinology; 2014
[Comparison between the centrifugation on MPA C10 (Roche Diagnostics) and the centrifugation according recommendations of GEHT (Groupe d'etude de l'hemostase et de la thrombose) for the daily hemostasis assays]: Author(s) : Flamant F, Borg J, Lenormand B, Le Cam-Duchez V,; Journal : Ann Biol Clin (Paris); 2014
Purkinje cells and Bergmann glia are primary targets of the TRalpha1 thyroid hormone receptor during mouse cerebellum postnatal development: Author(s) : Fauquier T, Chatonnet F, Picou F, Richard S, Fossat N, Aguilera N, Lamonerie T, Flamant F,; Journal : Development; 2014
Autonomous functions of murine thyroid hormone receptor TRalpha and TRbeta in cochlear hair cells: Author(s) : Dettling J, Franz C, Zimmermann U, Lee S, Bress A, Brandt N, Feil R, Pfister M, Engel J, Flamant F, Ruttiger L, Knipper M,; Journal : Mol Cell Endocrinol; 2014
Chondrocytes play a major role in the stimulation of bone growth by thyroid hormone: Author(s) : Desjardin C, Charles C, Benoist-Lasselin C, Riviere J, Gilles M, Chassande O, Morgenthaler C, Laloe D, Lecardonnel J, Flamant F, Legeai-Mallet L, Schibler L,; Journal : Endocrinology; 2014
Direct and indirect consequences on gene expression of a thyroid hormone receptor alpha 1 mutation restricted to Sertoli cells: Author(s) : Chatonnet F, Livera G, Fumel B, Fouch E, Flamant F,; Journal : Mol Reprod Dev; 2014
Thyroid hormone receptors: the challenge of elucidating isotype-specific functions and cell-specific response: Author(s) : Flamant F, Gauthier K,; Journal : Biochim Biophys Acta; 2013
Genome-wide analysis of thyroid hormone receptors shared and specific functions in neural cells: Author(s) : Chatonnet F, Guyot R, Benoit G, Flamant F,; Journal : Proc Natl Acad Sci U S A; 2013
[Thyroid hormone T3 triggers the developmental loss of axonal regenerative capacity]: Author(s) : Avci H, Flamant F, Dusart I,; Journal : Med Sci (Paris); 2013
A bimodal influence of thyroid hormone on cerebellum oligodendrocyte differentiation: Author(s) : Picou F, Fauquier T, Chatonnet F, Flamant F,; Journal : Mol Endocrinol; 2012
Genome-wide search reveals the existence of a limited number of thyroid hormone receptor alpha target genes in cerebellar neurons: Author(s) : Chatonnet F, Guyot R, Picou F, Bondesson M, Flamant F,; Journal : PLoS One; 2012
Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor alpha1 and kruppel-like factor 9 in Purkinje cells: Author(s) : Avci H, Lebrun C, Wehrle R, Doulazmi M, Chatonnet F, Morel M, Ema M, Vodjdani G, Sotelo C, Flamant F, Dusart I,; Journal : Proc Natl Acad Sci U S A; 2012
Severe impairment of cerebellum development in mice expressing a dominant-negative mutation inactivating thyroid hormone receptor alpha1 isoform: Author(s) : Fauquier T, Romero E, Picou F, Chatonnet F, Nguyen X, Quignodon L, Flamant F,; Journal : Dev Biol; 2011
Thyroid hormone action in cerebellum and cerebral cortex development: Author(s) : Chatonnet F, Picou F, Fauquier T, Flamant F,; Journal : J Thyroid Res; 2011
[Thyroid hormone and cerebellum development: direct and indirect effects?]: Author(s) : Chatonnet F, Fauquier T, Picou F, Guyot R, Flamant F,; Journal : Ann Endocrinol (Paris); 2011
Type 3 deiodinase deficiency causes spatial and temporal alterations in brain T3 signaling that are dissociated from serum thyroid hormone levels: Author(s) : Hernandez A, Quignodon L, Martinez M, Flamant F, St Germain D,; Journal : Endocrinology; 2010
Use of a new model of transgenic mice to clarify the respective functions of thyroid hormone receptors in vivo: Author(s) : Flamant F, Quignodon L,; Journal : Heart Fail Rev; 2010
Otx2 gene deletion in adult mouse retina induces rapid RPE dystrophy and slow photoreceptor degeneration: Author(s) : Beby F, Housset M, Fossat N, Le Greneur C, Flamant F, Godement P, Lamonerie T,; Journal : PLoS One; 2010
Deafness in TRbeta mutants is caused by malformation of the tectorial membrane: Author(s) : Winter H, Ruttiger L, Muller M, Kuhn S, Brandt N, Zimmermann U, Hirt B, Bress A, Sausbier M, Conscience A, Flamant F, Tian Y, Zuo J, Pfister M, Ruth P, Lowenheim H, Samarut J, Engel J, Knipper M,; Journal : J Neurosci; 2009
Interference of a mutant thyroid hormone receptor alpha1 with hepatic glucose metabolism: Author(s) : Vujovic M, Nordstrom K, Gauthier K, Flamant F, Visser T, Vennstrom B, Mittag J,; Journal : Endocrinology; 2009
[Thyroid hormone and its receptors: have mouse genetics clarified the situation?]: Author(s) : Flamant F, Quignodon L,; Journal : J Soc Biol; 2008
A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism: Author(s) : Bassett J, Williams A, Murphy E, Boyde A, Howell P, Swinhoe R, Archanco M, Flamant F, Samarut J, Costagliola S, Vassart G, Weiss R, Refetoff S, Williams G,; Journal : Mol Endocrinol; 2008
Peripheral circulation of the prion infectious agent in transgenic mice expressing the ovine prion protein gene in neurons only: Author(s) : Crozet C, Lezmi S, Flamant F, Samarut J, Baron T, Bencsik A,; Journal : J Infect Dis; 2007
Modeling the role of mid-wavelength cones in circadian responses to light: Author(s) : Dkhissi-Benyahya O, Gronfier C, De Vanssay W, Flamant F, Cooper H,; Journal : Neuron; 2007
Thyroid hormones signaling is getting more complex: STORMs are coming: Author(s) : Flamant F, Gauthier K, Samarut J,; Journal : Mol Endocrinol; 2007
A point mutation in the activation function 2 domain of thyroid hormone receptor alpha1 expressed after CRE-mediated recombination partially recapitulates hypothyroidism: Author(s) : Quignodon L, Vincent S, Winter H, Samarut J, Flamant F,; Journal : Mol Endocrinol; 2007
A combined approach identifies a limited number of new thyroid hormone target genes in post-natal mouse cerebellum: Author(s) : Quignodon L, Grijota-Martinez C, Compe E, Guyot R, Allioli N, Laperriere D, Walker R, Meltzer P, Mader S, Samarut J, Flamant F,; Journal : J Mol Endocrinol; 2007
International Union of Pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: thyroid hormone receptors: Author(s) : Flamant F, Baxter J, Forrest D, Refetoff S, Samuels H, Scanlan T, Vennstrom B, Samarut J,; Journal : Pharmacol Rev; 2006
The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification: Author(s) : Bonnafe E, Touka M, AitLounis A, Baas D, Barras E, Ucla C, Moreau A, Flamant F, Dubruille R, Couble P, Collignon J, Durand B, Reith W,; Journal : Mol Cell Biol; 2004
Both thyroid hormone receptor (TR)beta 1 and TR beta 2 isoforms contribute to the regulation of hypothalamic thyrotropin-releasing hormone: Author(s) : Dupre S, Guissouma H, Flamant F, Seugnet I, Scanlan T, Baxter J, Samarut J, Demeneix B, Becker N,; Journal : Endocrinology; 2004
Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life: Author(s) : Mai W, Janier M, Allioli N, Quignodon L, Chuzel T, Flamant F, Samarut J,; Journal : Proc Natl Acad Sci U S A; 2004
Thyroid hormone signaling is highly heterogeneous during pre- and postnatal brain development: Author(s) : Quignodon L, Legrand C, Allioli N, Guadano-Ferraz A, Bernal J, Samarut J, Flamant F,; Journal : J Mol Endocrinol; 2004
Thyroid hormone receptors: lessons from knockout and knock-in mutant mice: Author(s) : Flamant F, Samarut J,; Journal : Trends Endocrinol Metab; 2003
Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum: Author(s) : Poguet A, Legrand C, Feng X, Yen P, Meltzer P, Samarut J, Flamant F,; Journal : Dev Biol; 2003
Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice: Author(s) : Yen P, Feng X, Flamant F, Chen Y, Walker R, Weiss R, Chassande O, Samarut J, Refetoff S, Meltzer P,; Journal : EMBO Rep; 2003
Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors: Author(s) : Baas D, Legrand C, Samarut J, Flamant F,; Journal : Proc Natl Acad Sci U S A; 2002
Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene: Author(s) : Flamant F, Poguet A, Plateroti M, Chassande O, Gauthier K, Streichenberger N, Mansouri A, Samarut J,; Journal : Mol Endocrinol; 2002
Null mutant mice for thyroid hormone receptors: Author(s) : Gauthier K, Aubert D, Chassande O, Flamant F, Samarut J,; Journal : Methods Mol Biol; 2002
Florid plaques in ovine PrP transgenic mice infected with an experimental ovine BSE: Author(s) : Crozet C, Bencsik A, Flamant F, Lezmi S, Samarut J, Baron T,; Journal : EMBO Rep; 2001
Efficient transmission of two different sheep scrapie isolates in transgenic mice expressing the ovine PrP gene: Author(s) : Crozet C, Flamant F, Bencsik A, Aubert D, Samarut J, Baron T,; Journal : J Virol; 2001
A novel growth-factor-dependent myeloid cell line derived from mouse bone marrow cells contains progenitors endowed with high proliferative potential: Author(s) : Revol V, Tsuboi I, Flamant F, Samarut J, Blanchet J, Mouchiroud G,; Journal : Exp Hematol; 1999
Involvement of thyroid hormone and its alpha receptor in avian neurulation: Author(s) : Flamant F, Samarut J,; Journal : Dev Biol; 1998
Identification of transcripts initiated from an internal promoter in the c-erbA alpha locus that encode inhibitors of retinoic acid receptor-alpha and triiodothyronine receptor activities: Author(s) : Chassande O, Fraichard A, Gauthier K, Flamant F, Legrand C, Savatier P, Laudet V, Samarut J,; Journal : Mol Endocrinol; 1997
Vectors derived from avian leukosis and sarcoma viruses: Author(s) : Flamant F, Cosset F, Samarut J,; Journal : J Mol Med (Berl); 1995
Virofection: a one-step procedure for using replication-defective retrovirus vectors: Author(s) : Flamant F, Samarut J,; Journal : Virology; 1995
Replication-competent and -defective retrovirus vectors for oncogenic studies: Author(s) : Samarut J, Flamant F, Heard J,; Journal : Methods Enzymol; 1995
Virofection: a new procedure to achieve stable expression of genes transferred into early embryos: Author(s) : Flamant F, Demeneix B, Benoist C, Markossian-Belin S, Samarut J,; Journal : Int J Dev Biol; 1994
Importance of 3' non-coding sequences for efficient retrovirus-mediated gene transfer in avian cells revealed by self-inactivating vectors: Author(s) : Flamant F, Aubert D, Legrand C, Cosset F, Samarut J,; Journal : J Gen Virol; 1993

Navigation

Publications

Neuronal blockade of thyroid hormone signaling increases sensitivity to diet-induced obesity in adult male mice

Prenatal exposure to paraquat and nanoscaled TiO2 aerosols alters the gene expression of the developing brain

Brown adipocytes local response to thyroid hormone is required for adaptive thermogenesis in adult male mice

Functional definition of thyroid hormone response elements based on a synthetic STARR-seq screen

A disease-associated mutation in thyroid hormone receptor α1 causes hearing loss and sensory hair cell patterning defects in mice

An Atlas of Thyroid Hormone Receptors' Target Genes in Mouse Tissues

Assessment of pesticides capacity to act as agonists/antagonists of the thyroid hormone nuclear receptors

Central vs. Peripheral Action of Thyroid Hormone in Adaptive Thermogenesis: A Burning Topic

PRMT1 Is Critical for the Transcriptional Activity and the Stability of the Progesterone Receptor.

Two novel cases of resistance to thyroid hormone due to THRA mutation (RTHα)

A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons

Protocols for Studying How Thyroid Hormone Receptors Trigger Adaptive Thermogenesis in Mice.

Thyroid hormone in the regulation of hepatocellular carcinoma and its microenvironment.

Thyroid Hormone Receptor Alpha Deletion in ApoE-/- Mice Alters the Arterial Renin-Angiotensin System and Vascular Smooth Muscular Cell Cholesterol Metabolism

Regulation of T3 Availability in the Developing Brain: The Mouse Genetics Contribution

CRISPR/Cas9 Editing of the Mouse Thra Gene Produces Models with Variable Resistance to Thyroid Hormone

Two Protocols to Study the Interactions of Thyroid Hormone Receptors with Other Proteins and Chromatin

Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing.

Neuronal expression of a thyroid hormone receptor alpha mutation alters mouse behaviour

Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin

Genetic Investigation of Thyroid Hormone Receptor Function in the Developing and Adult Brain

Thyroid hormone signaling pathways. Time for a more precise nomenclature

Neuronal expression of a thyroid hormone receptor alpha mutation alters mouse behaviour

CRISPR/Cas9: a breakthrough in generating mouse models for endocrinologists

Futures Challenges in Thyroid Hormone Signaling Research

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

Unique features of a global human ectoparasite identified through sequencing of the bed bug genome

Thyroid Hormone Signaling in the Mouse Retina

TRalpha receptor mutations extend the spectrum of syndromes of reduced sensitivity to thyroid hormone

Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance

Editorial: "Thyroid Hormone in Brain and Brain Cells"

Human odontoblast-like cells produce nitric oxide with antibacterial activity upon TLR2 activation

A Novel Mutation in THRA Gene Associated With an Atypical Phenotype of Resistance to Thyroid Hormone

A temporary compendium of thyroid hormone target genes in brain

The targeted inactivation of TRbeta gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production

Deciphering direct and indirect influence of thyroid hormone with mouse genetics

Toxicogenomic analysis of the ability of brominated flame retardants TBBPA and BDE-209 to disrupt thyroid hormone signaling in neural cells

Nongenomic, TRbeta-dependent, thyroid hormone response gets genetic support

[Comparison between the centrifugation on MPA C10 (Roche Diagnostics) and the centrifugation according recommendations of GEHT (Groupe d'etude de l'hemostase et de la thrombose) for the daily hemostasis assays]

Purkinje cells and Bergmann glia are primary targets of the TRalpha1 thyroid hormone receptor during mouse cerebellum postnatal development

Autonomous functions of murine thyroid hormone receptor TRalpha and TRbeta in cochlear hair cells

Chondrocytes play a major role in the stimulation of bone growth by thyroid hormone

Direct and indirect consequences on gene expression of a thyroid hormone receptor alpha 1 mutation restricted to Sertoli cells

Thyroid hormone receptors: the challenge of elucidating isotype-specific functions and cell-specific response

Genome-wide analysis of thyroid hormone receptors shared and specific functions in neural cells

[Thyroid hormone T3 triggers the developmental loss of axonal regenerative capacity]

A bimodal influence of thyroid hormone on cerebellum oligodendrocyte differentiation

Genome-wide search reveals the existence of a limited number of thyroid hormone receptor alpha target genes in cerebellar neurons

Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor alpha1 and kruppel-like factor 9 in Purkinje cells

Severe impairment of cerebellum development in mice expressing a dominant-negative mutation inactivating thyroid hormone receptor alpha1 isoform

Thyroid hormone action in cerebellum and cerebral cortex development

[Thyroid hormone and cerebellum development: direct and indirect effects?]

Type 3 deiodinase deficiency causes spatial and temporal alterations in brain T3 signaling that are dissociated from serum thyroid hormone levels

Use of a new model of transgenic mice to clarify the respective functions of thyroid hormone receptors in vivo

Otx2 gene deletion in adult mouse retina induces rapid RPE dystrophy and slow photoreceptor degeneration

Deafness in TRbeta mutants is caused by malformation of the tectorial membrane

Interference of a mutant thyroid hormone receptor alpha1 with hepatic glucose metabolism

[Thyroid hormone and its receptors: have mouse genetics clarified the situation?]

A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism

Peripheral circulation of the prion infectious agent in transgenic mice expressing the ovine prion protein gene in neurons only

Modeling the role of mid-wavelength cones in circadian responses to light

Thyroid hormones signaling is getting more complex: STORMs are coming

A point mutation in the activation function 2 domain of thyroid hormone receptor alpha1 expressed after CRE-mediated recombination partially recapitulates hypothyroidism

A combined approach identifies a limited number of new thyroid hormone target genes in post-natal mouse cerebellum

International Union of Pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: thyroid hormone receptors

The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification

Both thyroid hormone receptor (TR)beta 1 and TR beta 2 isoforms contribute to the regulation of hypothalamic thyrotropin-releasing hormone

Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life

Thyroid hormone signaling is highly heterogeneous during pre- and postnatal brain development

Thyroid hormone receptors: lessons from knockout and knock-in mutant mice

Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum

Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice

Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors

Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene

Null mutant mice for thyroid hormone receptors

Florid plaques in ovine PrP transgenic mice infected with an experimental ovine BSE

Efficient transmission of two different sheep scrapie isolates in transgenic mice expressing the ovine PrP gene

A novel growth-factor-dependent myeloid cell line derived from mouse bone marrow cells contains progenitors endowed with high proliferative potential