Publications

The Hox transcription factor Ultrabithorax binds RNA and regulates co-transcriptional splicing through an interplay with RNA polymerase II: Author(s) : Carnesecchi J, Boumpas P, van Nierop Y Sanchez P, Domsch K, Pinto H, Borges Pinto P, Lohmann I,; Journal : Nucleic Acids Res; 2021
In-Depth Annotation of the Drosophila Bithorax-Complex Reveals the Presence of Several Alternative ORFs That Could Encode for Motif-Rich Peptides: Author(s) : Naville M, Merabet S,; Journal : Cells; 2021
Developmental Robustness: The Haltere Case in Drosophila: Author(s) : Giraud G, Paul R, Duffraisse M, Khan S, Shashidhara L, Merabet S,; Journal : Front Cell Dev Biol; 2021
Bimolecular Fluorescence Complementation (BiFC) and Multiplexed Imaging of Protein-Protein Interactions in Human Living Cells: Author(s) : Jia Y, Bleicher F, Reboulet J, Merabet S,; Journal : Methods Mol Biol; 2021
Hox dosage contributes to flight appendage morphology in Drosophila: Author(s) : Paul R, Giraud G, Domsch K, Duffraisse M, Marmigère F, Khan S, Vanderperre S, Lohmann I, Stoks R, Shashidhara L, Merabet S,; Journal : Nat Commun; 2021
LACC1 deficiency links juvenile arthritis with autophagy and metabolism in macrophages: Author(s) : Omarjee O, Mathieu A, Quiniou G, Moreews M, Ainouze M, Frachette C, Melki I, Dumaine C, Gerfaud-Valentin M, Duquesne A, Kallinich T, Tahir Turanli E, Malcus C, Viel S, Pescarmona R, Georgin-Lavialle S, Jamilloux Y, Larbre J, Sarrabay G, Magnotti F, Rice G, Bleicher F, Reboulet J, Merabet S, Henry T, Crow Y, Faure M, Walzer T, Belot A,; Journal : J Exp Med; 2021
Role of a versatile peptide motif controlling Hox nuclear export and autophagy in the Drosophila fat body: Author(s) : Duffraisse M, Paul R, Carnesecchi J, Hudry B, Banreti A, Reboulet J, Ajuria L, Lohmann I, Merabet S,; Journal : J. Cell. Sci.; 2020
Cooperation of axial and sex specific information controls Drosophila female genitalia growth by regulating the Decapentaplegic pathway: Author(s) : Romero-Pozuelo J, Foronda D, Martin P, Hudry B, Merabet S, Graba Y, Sanchez-Herrero E,; Journal : Dev Biol; 2019
The human HOXA9 protein uses paralog-specific residues of the homeodomain to interact with TALE-class cofactors: Author(s) : Dard A, Jia Y, Reboulet J, Bleicher F, Lavau C, Merabet S,; Journal : Scientific Reports; 2019
A systematic survey of HOX and TALE expression profiling in human cancers.: Author(s) : Jia Y, Bleicher F, Merabet S,; Journal : Int J Dev Biol; 2018
Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila: Author(s) : Bischof J, Duffraisse M, Furger E, Ajuria L, Giraud G, Vanderperre S, Paul R, Björklund M, Ahr D, Ahmed A, Spinelli L, Brun C, Basler K, Merabet S,; Journal : eLife; 2018
Human HOX Proteins Use Diverse and Context-Dependent Motifs to Interact with TALE Class Cofactors: Author(s) : Dard A, Reboulet J, Jia Y, Bleicher F, Duffraisse M, Vanaker J, Forcet C, Merabet S,; Journal : Cell Rep; 2018
Homeodomain proteins in action: similar DNA binding preferences, highly variable connectivity: Author(s) : Bobola N, Merabet S,; Journal : Curr Opin Genet Dev; 2017
To Be Specific or Not: The Critical Relationship Between Hox And TALE Proteins: Author(s) : Merabet S, Mann R,; Journal : Trends Genet; 2016
Inhibitory activities of short linear motifs underlie Hox interactome specificity in vivo: Author(s) : Baeza M, Viala S, Heim M, Dard A, Hudry B, Duffraisse M, Rogulja-Ortmann A, Brun C, Merabet S,; Journal : Elife; 2015
The TALE face of Hox proteins in animal evolution: Author(s) : Merabet S, Galliot B,; Journal : Front Genet; 2015
Toward a new twist in Hox and TALE DNA-binding specificity: Author(s) : Merabet S, Lohmann I,; Journal : Dev Cell; 2015
Drosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19: Author(s) : Boube M, Hudry B, Immarigeon C, Carrier Y, Bernat-Fabre S, Merabet S, Graba Y, Bourbon H, Cribbs D,; Journal : PLoS Genet; 2014
Bimolecular fluorescence complementation (BiFC) in live Drosophila embryos: Author(s) : Duffraisse M, Hudry B, Merabet S,; Journal : Methods Mol Biol; 2014
Molecular insights into the origin of the Hox-TALE patterning system: Author(s) : Hudry B, Thomas-Chollier M, Volovik Y, Duffraisse M, Dard A, Frank D, Technau U, Merabet S,; Journal : Elife; 2014
Tracking context-specific transcription factors regulating hox activity: Author(s) : Merabet S, Dard A,; Journal : Dev Dyn; 2014
Antagonism versus cooperativity with TALE cofactors at the base of the functional diversification of Hox protein function: Author(s) : Rivas M, Espinosa-Vazquez J, Sambrani N, Greig S, Merabet S, Graba Y, Hombria J,; Journal : PLoS Genet; 2013
Distinct molecular strategies for Hox-mediated limb suppression in Drosophila: from cooperativity to dispensability/antagonism in TALE partnership: Author(s) : Sambrani N, Hudry B, Maurel-Zaffran C, Zouaz A, Mishra R, Merabet S, Graba Y,; Journal : PLoS Genet; 2013
Hox transcriptional specificity despite a single class of cofactors: are flexible interaction modes the key? Plasticity in Hox/PBC interaction modes as a common molecular strategy for shaping Hox transcriptional activities: Author(s) : Merabet S, Hudry B,; Journal : Bioessays; 2013
Hox proteins display a common and ancestral ability to diversify their interaction mode with the PBC class cofactors: Author(s) : Hudry B, Remacle S, Delfini M, Rezsohazy R, Graba Y, Merabet S,; Journal : PLoS Biol; 2012
Visualization of protein interactions in living Drosophila embryos by the bimolecular fluorescence complementation assay: Author(s) : Hudry B, Viala S, Graba Y, Merabet S,; Journal : BMC Biol; 2011
On the border of the homeotic function: re-evaluating the controversial role of cofactor-recruiting motifs: the role of cofactor-recruiting motifs in conferring Hox evolutionary flexibility may critically depend on the protein environment: Author(s) : Merabet S, Hudry B,; Journal : Bioessays; 2011
Insights into Hox protein function from a large scale combinatorial analysis of protein domains: Author(s) : Merabet S, Litim-Mecheri I, Karlsson D, Dixit R, Saadaoui M, Monier B, Brun C, Thor S, Vijayraghavan K, Perrin L, Pradel J, Graba Y,; Journal : PLoS Genet; 2011
Selection of distinct Hox-Extradenticle interaction modes fine-tunes Hox protein activity: Author(s) : Saadaoui M, Merabet S, Litim-Mecheri I, Arbeille E, Sambrani N, Damen W, Brena C, Pradel J, Graba Y,; Journal : Proc Natl Acad Sci U S A; 2011
Regulation of Hox activity: insights from protein motifs: Author(s) : Merabet S, Sambrani N, Pradel J, Graba Y,; Journal : Adv Exp Med Biol; 2010
Classification of sequence signatures: a guide to Hox protein function: Author(s) : Merabet S, Hudry B, Saadaoui M, Graba Y,; Journal : Bioessays; 2009
A unique Extradenticle recruitment mode in the Drosophila Hox protein Ultrabithorax: Author(s) : Merabet S, Saadaoui M, Sambrani N, Hudry B, Pradel J, Affolter M, Graba Y,; Journal : Proc Natl Acad Sci U S A; 2007
Recognition of distinct target sites by a unique Labial/Extradenticle/Homothorax complex: Author(s) : Ebner A, Cabernard C, Affolter M, Merabet S,; Journal : Development; 2005
The Drosophila Extradenticle and Homothorax selector proteins control branchless/FGF expression in mesodermal bridge-cells: Author(s) : Merabet S, Ebner A, Affolter M,; Journal : EMBO Rep; 2005
Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis: Author(s) : Merabet S, Hombria J, Hu N, Pradel J, Graba Y,; Journal : Development; 2005
Getting a molecular grasp on Hox contextual activity: Author(s) : Merabet S, Pradel J, Graba Y,; Journal : Trends Genet; 2005
Tgfbeta signaling acts on a Hox response element to confer specificity and diversity to Hox protein function: Author(s) : Grienenberger A, Merabet S, Manak J, Iltis I, Fabre A, Berenger H, Scott M, Pradel J, Graba Y,; Journal : Development; 2003
The hexapeptide and linker regions of the AbdA Hox protein regulate its activating and repressive functions: Author(s) : Merabet S, Kambris Z, Capovilla M, Berenger H, Pradel J, Graba Y,; Journal : Dev Cell; 2003
A green fluorescent protein reporter genetic screen that identifies modifiers of Hox gene function in the Drosophila embryo: Author(s) : Merabet S, Catala F, Pradel J, Graba Y,; Journal : Genetics; 2002
Modes d'action des protéines Hox: des interrogations nouvelles.: Author(s) : Merabet S, Grienenberger A, Pradel J, Graba Y,; Journal : Médecine/Sciences; 2001
Distinct hox protein sequences determine specificity in different tissues: Author(s) : Chauvet S, Merabet S, Bilder D, Scott M, Pradel J, Graba Y,; Journal : Proc Natl Acad Sci U S A; 2000

Navigation

Publications

The Hox transcription factor Ultrabithorax binds RNA and regulates co-transcriptional splicing through an interplay with RNA polymerase II

In-Depth Annotation of the Drosophila Bithorax-Complex Reveals the Presence of Several Alternative ORFs That Could Encode for Motif-Rich Peptides

Developmental Robustness: The Haltere Case in Drosophila

Bimolecular Fluorescence Complementation (BiFC) and Multiplexed Imaging of Protein-Protein Interactions in Human Living Cells

Hox dosage contributes to flight appendage morphology in Drosophila

LACC1 deficiency links juvenile arthritis with autophagy and metabolism in macrophages

Role of a versatile peptide motif controlling Hox nuclear export and autophagy in the Drosophila fat body

Cooperation of axial and sex specific information controls Drosophila female genitalia growth by regulating the Decapentaplegic pathway

The human HOXA9 protein uses paralog-specific residues of the homeodomain to interact with TALE-class cofactors

A systematic survey of HOX and TALE expression profiling in human cancers.

Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila

Human HOX Proteins Use Diverse and Context-Dependent Motifs to Interact with TALE Class Cofactors

Homeodomain proteins in action: similar DNA binding preferences, highly variable connectivity

To Be Specific or Not: The Critical Relationship Between Hox And TALE Proteins

Inhibitory activities of short linear motifs underlie Hox interactome specificity in vivo

The TALE face of Hox proteins in animal evolution

Toward a new twist in Hox and TALE DNA-binding specificity

Drosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19

Bimolecular fluorescence complementation (BiFC) in live Drosophila embryos

Molecular insights into the origin of the Hox-TALE patterning system

Tracking context-specific transcription factors regulating hox activity

Antagonism versus cooperativity with TALE cofactors at the base of the functional diversification of Hox protein function

Distinct molecular strategies for Hox-mediated limb suppression in Drosophila: from cooperativity to dispensability/antagonism in TALE partnership

Hox transcriptional specificity despite a single class of cofactors: are flexible interaction modes the key? Plasticity in Hox/PBC interaction modes as a common molecular strategy for shaping Hox transcriptional activities

Hox proteins display a common and ancestral ability to diversify their interaction mode with the PBC class cofactors

Visualization of protein interactions in living Drosophila embryos by the bimolecular fluorescence complementation assay

On the border of the homeotic function: re-evaluating the controversial role of cofactor-recruiting motifs: the role of cofactor-recruiting motifs in conferring Hox evolutionary flexibility may critically depend on the protein environment

Insights into Hox protein function from a large scale combinatorial analysis of protein domains

Selection of distinct Hox-Extradenticle interaction modes fine-tunes Hox protein activity

Regulation of Hox activity: insights from protein motifs

Classification of sequence signatures: a guide to Hox protein function

A unique Extradenticle recruitment mode in the Drosophila Hox protein Ultrabithorax

Recognition of distinct target sites by a unique Labial/Extradenticle/Homothorax complex

The Drosophila Extradenticle and Homothorax selector proteins control branchless/FGF expression in mesodermal bridge-cells

Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis

Getting a molecular grasp on Hox contextual activity

Tgfbeta signaling acts on a Hox response element to confer specificity and diversity to Hox protein function

The hexapeptide and linker regions of the AbdA Hox protein regulate its activating and repressive functions

A green fluorescent protein reporter genetic screen that identifies modifiers of Hox gene function in the Drosophila embryo

Modes d'action des protéines Hox: des interrogations nouvelles.

Distinct hox protein sequences determine specificity in different tissues

Contacts

Ressources

Outils