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Soutenance HDR : Julie Carnesecchi

Quand ? Le 25/10/2023,
de 02:00 à 05:00
Où ? Salle des thèses
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Julie Carnesecchi soutiendra son Habilitation à Diriger des Recherches le mercredi 25 octobre 2023 dans la salle des thèse, intitulée :

 "Integrating transcription and mRNA processing networks into cell fate decision"

Abstract:

While the current view states that Transcription Factors (TFs) act on DNA regulatory elements to deploy precise gene programs, an emerging concept proposes that TFs also bind RNA and regulate mRNA biogenesis to promote molecular and cellular diversity. Yet, how the RNA regulatory functions of TFs contribute to their key role in cell fates remains puzzling. From in vitro interaction to tissue development, the HDR presentation will survey my previous work and our latest findings focusing on the splicing function and RNA-binding ability of the homeodomain TFs, using Drosophila muscle development as a paradigm of cell fate decisions.