Annuaire
Tissue regeneration
|
Zebrafish, as other organisms such as salamander and crustacean, present a high capacity to regenerate different parts of their body including the heart, nervous tissue and fin. We thus used the zebrafish caudal fin model of regeneration (i) to better understand the existing divergences between mammals and such organisms and (ii) to investigate the role of various extracellular matrix proteins in regeneration capacity. We particularly focus on collagens XIV and XII, Matrix Metalloproteinases and their tissue Inhibitors (TIMPs) and on the identification of the cells responsible for the production and secretion of these proteins at the site of amputation. |
|---|