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            © V. Moncorgé

Optimum growth via IGF-1 (Insulin-like growth factor 1) is ensured by intestinal microbiota, even in undernutrition. This has been demonstrated by F.Leulier's team and colleagues and published in Science.

Link to press release.



Drosophila larvae (artistic view)-B. Erkosar

Commensal bacteria are beneficial for the growth of their host via activation of peptidases but this effect is lost in the presence of pathogens. Link to thepublication in Cell Host and Microbe authored by the team of F. Leulier.

mdaillebronzeCNRS.gif Hugo Aguilaniu PI of "Aging, reproduction and metabolism"team received the CNRS' bronze medal in 2015. LogoBPAERR_480x685.gif

A new receptor for Bisphenol A.

Press release in English (pdf).
Link to the publication.


(click to enlarge)

Team of S. Merabet has shown that specificity of interaction between Hox proteins and transcription factors relies on conserved short linear motifs.
Results are published in eLife:
Baeza M et al. eLife. 2015 Apr 14;4.

mdaillebronzeCNRS.gif Two team leaders, François Leulier and Samir Merabet received the CNRS' bronze medal in 2013.


  (click to enlarge)

Using slight variations in the amount of rate-limiting enzymes important in Retinoic Acid (RA) pathway V. Laudet and colleagues demonstrate that RA availability influences tooth number in Cyprinids. They publish their results in Proceedings Royal Society B.

BPA structure Physiological effects of Bisphenol A (BPA) are studied at the IGFL. This  widely used chemical compound induces malformations of the inner ear in zebrafish and has effects on the reproductive system...more here (in French).  



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