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Molecular and epigenetic regulation of biological clocks

 

 

Current lab members:

Laurence Canaple (IR, CNRS)

Helene Boyer (PhD, ENS)

Eric Folco (Postdoc)

Nicolas McAdams (M2 stagiare)

Lies Chikhaoui (M1 stagiare)

co-supervisor : Lorrie Ramos (PhD student IAB, Grenoble)

 

Former trainees:

Shannin Arenales Castillo (Masters student year 1), ENS Biosciences

Isahak Saidi (Masters student, year 2) ; currently PhD student at Champalimaud Neuroscience Programme.

Aysegul Ors (PhD student IAB, Grenoble and Bilkent University) (Thesis writing!)

Stella Chausheva (PhD student, Medical University of Vienna)

 

 

 

Key References:

1. Ors A, Papin C, Favier B, Roulland Y, Dalkara D, Ozturk M, Hamiche A, Dimitrov S and Padmanabhan K#. Histone H3.3 regulates
    mitotic progression in mouse embryonic fibroblasts. Biochemistry and Cell Biology, 2017 doi :10.1139/bcb-2016-0190

2. Roulland Y , Ouararhni K , Naidenov M , Ramos L , Shuaib M , Syed SH , Lone IN, Boopathi R, Fontaine E , Papai G ,Tachiwana H,
    Gautier T , Skoufias D , Padmanabhan K , Bednar J , Kurumizaka H,  Schultz P, Angelov D , Hamiche A & Dimitrov S. The flexible ends
    of CENP-A nucleosome are required for mitotic fidelity. Molecular Cell. 32081-7(16).  2016

3. Obri A, Ouararhni K, Papin C, Diebold ML, Padmanabhan K, Marek M, Stoll I, Roy L, Reilly PT, Mak TW, Dimitrov S, Romier C and
    Hamiche A. ANP32E is a histone chaperone that removes H2A.Z from chromatin. Nature. 505: 648-53. 2014

4. Padmanabhan K, Robles M, Westerling T and Weitz CJ. Feedback regulation of transcriptional termination by the mammalian circadian       clock PERIOD complex. Science. 337: 599-602. 2012


5. Robles M, Boyault C, Knutti D, Padmanabhan K and Weitz CJ. Identification of RACK1 and protein kinase Calpha as integral      
    components of the mammalian circadian clock. Science. 327: 463-6, 2010.

The lab's research benefits from funding from:

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