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Molecular and epigenetic regulation of biological clocks



Current lab members:

Laurence Canaple (IR, CNRS)

Helene Boyer (PhD, ENS)

Eric Folco (Postdoc)

Nicolas McAdams (M2 stagiare)

Lies Chikhaoui (M1 stagiare)


Former trainees:

Shannin Arenale Castillo (M1)

Isahak Saidi (M2) 


Key References:

1. Roulland Y , Ouararhni K , Naidenov M , Ramos L , Shuaib M , Syed SH , Lone IN, Boopathi R, Fontaine E , Papai G ,Tachiwana H, Gautier T , Skoufias D , Padmanabhan K , Bednar J , Kurumizaka H,  Schultz P, Angelov D , Hamiche A & Dimitrov S. The flexible ends of CENP-A nucleosome are required for mitotic fidelity. Molecular Cell. 32081-7(16).  2016

2.      Obri A, Ouararhni K, Papin C, Diebold ML, Padmanabhan K, Marek M, Stoll I, Roy L, Reilly PT, Mak TW, Dimitrov S, Romier C and Hamiche A. ANP32E is a histone chaperone that removes H2A.Z from chromatin. Nature. 505: 648-53. 2014

3.     Padmanabhan K, Robles M, Westerling T and Weitz CJ. Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex. Science. 337: 599-602. 2012

4.     Robles M, Boyault C, Knutti D, Padmanabhan K and Weitz CJ. Identification of RACK1 and protein kinase Calpha as integral components of the mammalian circadian clock. Science. 327: 463-6, 2010.

The lab's research benefits from funding from:

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