Skip to content. | Skip to navigation

Personal tools

Sections

Publications

Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing.

Author(s) : Teixeira M, Py B, Bosc C, Laubreton D, Moutin M, Marvel J, Flamant F, Markossian S,
Journal : Sci Rep
2018

Neuronal expression of a thyroid hormone receptor alpha mutation alters mouse behaviour

Author(s) : Richard S, Aguilera N, Thevenet M, Dkhissi-Benyahya O, Flamant F,
Journal : Behav Brain Res
2017

Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin

Author(s) : Guan W, Guyot R, Samarut J, Flamant F, Wong J, Gauthier K,
Journal : Proc Natl Acad Sci U S A
2017

Genetic Investigation of Thyroid Hormone Receptor Function in the Developing and Adult Brain

Author(s) : Flamant F, Gauthier K, Richard S,
Journal : Curr Top Dev Biol
2017

Thyroid hormone signaling pathways. Time for a more precise nomenclature

Author(s) : Flamant F, Cheng S, Hollenberg A, Moeller L, Samarut J, Wondisford F, Yen P, Refetoff S,
Journal : Endocrinology
2017

Neuronal expression of a thyroid hormone receptor alpha mutation alters mouse behaviour

Author(s) : Richard S, Aguilera N, Thevenet M, Dkhissi-Benyahya O, Flamant F,
Journal : Behav Brain Res
2016

CRISPR/Cas9: a breakthrough in generating mouse models for endocrinologists

Author(s) : Markossian S, Flamant F,
Journal : J Mol Endocrinol
2016

Futures Challenges in Thyroid Hormone Signaling Research

Author(s) : Flamant F,
Journal : Front Endocrinol (Lausanne)
2016

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

Author(s) : Finan B, Clemmensen C, Zhu Z, Stemmer K, Gauthier K, Muller L, De Angelis M, Moreth K, Neff F, Perez-Tilve D, Fischer K, Lutter D, Sanchez-Garrido M, Liu P, Tuckermann J, Malehmir M, Healy M, Weber A, Heikenwalder M, Jastroch M, Kleinert M, Jall S, Brandt S, Flamant F, Schramm K, Biebermann H, Doring Y, Weber C, Habegger K, Keuper M, Gelfanov V, Liu F, Kohrle J, Rozman J, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Hofmann S, Yang B, Tschop M, DiMarchi R, Muller T,
Journal : Cell
2016

Unique features of a global human ectoparasite identified through sequencing of the bed bug genome

Author(s) : Benoit J, Adelman Z, Reinhardt K, Dolan A, Poelchau M, Jennings E, Szuter E, Hagan R, Gujar H, Shukla J, Zhu F, Mohan M, Nelson D, Rosendale A, Derst C, Resnik V, Wernig S, Menegazzi P, Wegener C, Peschel N, Hendershot J, Blenau W, Predel R, Johnston P, Ioannidis P, Waterhouse R, Nauen R, Schorn C, Ott M, Maiwald F, Johnston J, Gondhalekar A, Scharf M, Peterson B, Raje K, Hottel B, Armisen D, Crumiere A, Refki P, Santos M, Sghaier E, Viala S, Khila A, Ahn S, Childers C, Lee C, Lin H, Hughes D, Duncan E, Murali S, Qu J, Dugan S, Lee S, Chao H, Dinh H, Han Y, Doddapaneni H, Worley K, Muzny D, Wheeler D, Panfilio K, Vargas Jentzsch I, Vargo E, Booth W, Friedrich M, Weirauch M, Anderson M, Jones J, Mittapalli O, Zhao C, Zhou J, Evans J, Attardo G, Robertson H, Zdobnov E, Ribeiro J, Gibbs R, Werren J, Palli S, Schal C, Richards S,
Journal : Nat Commun
2016

Thyroid Hormone Signaling in the Mouse Retina

Author(s) : Arbogast P, Flamant F, Godement P, Glosmann M, Peichl L,
Journal : PLoS One
2016

TRalpha receptor mutations extend the spectrum of syndromes of reduced sensitivity to thyroid hormone

Author(s) : Vlaeminck-Guillem V, Espiard S, Flamant F, Wemeau J,
Journal : Presse Med
2015

Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance

Author(s) : Ozmadenci D, Feraud O, Markossian S, Kress E, Ducarouge B, Gibert B, Ge J, Durand I, Gadot N, Plateroti M, Bennaceur-Griscelli A, Scoazec J, Gil J, Deng H, Bernet A, Mehlen P, Lavial F,
Journal : Nat Commun
2015

Editorial: "Thyroid Hormone in Brain and Brain Cells"

Author(s) : Flamant F, Koibuchi N, Bernal J,
Journal : Front Endocrinol (Lausanne)
2015

Human odontoblast-like cells produce nitric oxide with antibacterial activity upon TLR2 activation

Author(s) : Farges J, Bellanger A, Ducret M, Aubert-Foucher E, Richard B, Alliot-Licht B, Bleicher F, Carrouel F,
Journal : Front Physiol
2015

A Novel Mutation in THRA Gene Associated With an Atypical Phenotype of Resistance to Thyroid Hormone

Author(s) : Espiard S, Savagner F, Flamant F, Vlaeminck-Guillem V, Guyot R, Munier M, d'Herbomez M, Bourguet W, Pinto G, Rose C, Rodien P, Wemeau J,
Journal : J Clin Endocrinol Metab
2015

A temporary compendium of thyroid hormone target genes in brain

Author(s) : Chatonnet F, Flamant F, Morte B,
Journal : Biochim Biophys Acta
2015

The targeted inactivation of TRbeta gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production

Author(s) : Selmi-Ruby S, Bouazza L, Obregon M, Conscience A, Flamant F, Samarut J, Borson-Chazot F, Rousset B,
Journal : Endocrinology
2014

Deciphering direct and indirect influence of thyroid hormone with mouse genetics

Author(s) : Picou F, Fauquier T, Chatonnet F, Richard S, Flamant F,
Journal : Mol Endocrinol
2014

Toxicogenomic analysis of the ability of brominated flame retardants TBBPA and BDE-209 to disrupt thyroid hormone signaling in neural cells

Author(s) : Guyot R, Chatonnet F, Gillet B, Hughes S, Flamant F,
Journal : Toxicology
2014

Nongenomic, TRbeta-dependent, thyroid hormone response gets genetic support

Author(s) : Gauthier K, Flamant F,
Journal : Endocrinology
2014

[Comparison between the centrifugation on MPA C10 (Roche Diagnostics) and the centrifugation according recommendations of GEHT (Groupe d'etude de l'hemostase et de la thrombose) for the daily hemostasis assays]

Author(s) : Flamant F, Borg J, Lenormand B, Le Cam-Duchez V,
Journal : Ann Biol Clin (Paris)
2014

Purkinje cells and Bergmann glia are primary targets of the TRalpha1 thyroid hormone receptor during mouse cerebellum postnatal development

Author(s) : Fauquier T, Chatonnet F, Picou F, Richard S, Fossat N, Aguilera N, Lamonerie T, Flamant F,
Journal : Development
2014

Autonomous functions of murine thyroid hormone receptor TRalpha and TRbeta in cochlear hair cells

Author(s) : Dettling J, Franz C, Zimmermann U, Lee S, Bress A, Brandt N, Feil R, Pfister M, Engel J, Flamant F, Ruttiger L, Knipper M,
Journal : Mol Cell Endocrinol
2014

Chondrocytes play a major role in the stimulation of bone growth by thyroid hormone

Author(s) : Desjardin C, Charles C, Benoist-Lasselin C, Riviere J, Gilles M, Chassande O, Morgenthaler C, Laloe D, Lecardonnel J, Flamant F, Legeai-Mallet L, Schibler L,
Journal : Endocrinology
2014

Direct and indirect consequences on gene expression of a thyroid hormone receptor alpha 1 mutation restricted to Sertoli cells

Author(s) : Chatonnet F, Livera G, Fumel B, Fouch E, Flamant F,
Journal : Mol Reprod Dev
2014

Thyroid hormone receptors: the challenge of elucidating isotype-specific functions and cell-specific response

Author(s) : Flamant F, Gauthier K,
Journal : Biochim Biophys Acta
2013

Genome-wide analysis of thyroid hormone receptors shared and specific functions in neural cells

Author(s) : Chatonnet F, Guyot R, Benoit G, Flamant F,
Journal : Proc Natl Acad Sci U S A
2013

[Thyroid hormone T3 triggers the developmental loss of axonal regenerative capacity]

Author(s) : Avci H, Flamant F, Dusart I,
Journal : Med Sci (Paris)
2013

A bimodal influence of thyroid hormone on cerebellum oligodendrocyte differentiation

Author(s) : Picou F, Fauquier T, Chatonnet F, Flamant F,
Journal : Mol Endocrinol
2012

Genome-wide search reveals the existence of a limited number of thyroid hormone receptor alpha target genes in cerebellar neurons

Author(s) : Chatonnet F, Guyot R, Picou F, Bondesson M, Flamant F,
Journal : PLoS One
2012

Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor alpha1 and kruppel-like factor 9 in Purkinje cells

Author(s) : Avci H, Lebrun C, Wehrle R, Doulazmi M, Chatonnet F, Morel M, Ema M, Vodjdani G, Sotelo C, Flamant F, Dusart I,
Journal : Proc Natl Acad Sci U S A
2012

Severe impairment of cerebellum development in mice expressing a dominant-negative mutation inactivating thyroid hormone receptor alpha1 isoform

Author(s) : Fauquier T, Romero E, Picou F, Chatonnet F, Nguyen X, Quignodon L, Flamant F,
Journal : Dev Biol
2011

Thyroid hormone action in cerebellum and cerebral cortex development

Author(s) : Chatonnet F, Picou F, Fauquier T, Flamant F,
Journal : J Thyroid Res
2011

[Thyroid hormone and cerebellum development: direct and indirect effects?]

Author(s) : Chatonnet F, Fauquier T, Picou F, Guyot R, Flamant F,
Journal : Ann Endocrinol (Paris)
2011

Type 3 deiodinase deficiency causes spatial and temporal alterations in brain T3 signaling that are dissociated from serum thyroid hormone levels

Author(s) : Hernandez A, Quignodon L, Martinez M, Flamant F, St Germain D,
Journal : Endocrinology
2010

Use of a new model of transgenic mice to clarify the respective functions of thyroid hormone receptors in vivo

Author(s) : Flamant F, Quignodon L,
Journal : Heart Fail Rev
2010

Otx2 gene deletion in adult mouse retina induces rapid RPE dystrophy and slow photoreceptor degeneration

Author(s) : Beby F, Housset M, Fossat N, Le Greneur C, Flamant F, Godement P, Lamonerie T,
Journal : PLoS One
2010

Deafness in TRbeta mutants is caused by malformation of the tectorial membrane

Author(s) : Winter H, Ruttiger L, Muller M, Kuhn S, Brandt N, Zimmermann U, Hirt B, Bress A, Sausbier M, Conscience A, Flamant F, Tian Y, Zuo J, Pfister M, Ruth P, Lowenheim H, Samarut J, Engel J, Knipper M,
Journal : J Neurosci
2009

Interference of a mutant thyroid hormone receptor alpha1 with hepatic glucose metabolism

Author(s) : Vujovic M, Nordstrom K, Gauthier K, Flamant F, Visser T, Vennstrom B, Mittag J,
Journal : Endocrinology
2009

[Thyroid hormone and its receptors: have mouse genetics clarified the situation?]

Author(s) : Flamant F, Quignodon L,
Journal : J Soc Biol
2008

A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism

Author(s) : Bassett J, Williams A, Murphy E, Boyde A, Howell P, Swinhoe R, Archanco M, Flamant F, Samarut J, Costagliola S, Vassart G, Weiss R, Refetoff S, Williams G,
Journal : Mol Endocrinol
2008

A point mutation in the activation function 2 domain of thyroid hormone receptor alpha1 expressed after CRE-mediated recombination partially recapitulates hypothyroidism

Author(s) : Quignodon L, Vincent S, Winter H, Samarut J, Flamant F,
Journal : Mol Endocrinol
2007

A combined approach identifies a limited number of new thyroid hormone target genes in post-natal mouse cerebellum

Author(s) : Quignodon L, Grijota-Martinez C, Compe E, Guyot R, Allioli N, Laperriere D, Walker R, Meltzer P, Mader S, Samarut J, Flamant F,
Journal : J Mol Endocrinol
2007