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Publications IGFL

Enhancer-promoter interactions form independently of genomic distance and are functional across TAD boundaries

Author(s) : Borges Pinto P, Grasso A, Balasubramanian D, Vincent S, Tarayre H, Lajoignie D, Ghavi-Helm Y,
Journal : NAR

Zeb1 represses TCR signaling, promotes the proliferation of T cell progenitors and is essential for NK1.1+ T cell development

Author(s) : Zhang J, Wencker M, Marliac Q, Berton A, Hasan U, Schneider R, Laubreton D, Cherrier D, Mathieu A, Rey A, Jiang W, Caramel J, Genestier L, Marçais A, Marvel J, Ghavi-Helm Y, Walzer T,
Journal : Cell Mol Immunol

3D genome organisation in Drosophila

Author(s) : Moretti C, Stevant I, Ghavi-Helm Y,
Journal : Briefings in Functional Genomics

Functional consequences of chromosomal rearrangements on gene expression: not so deleterious after all?

Author(s) : Ghavi-Helm Y,
Journal : Journal of Molecular Biology

Highly rearranged chromosomes reveal uncoupling between genome topology and gene expression

Author(s) : Ghavi-Helm Y, Jankowski A, Meiers S, Viales R, Korbel J, Furlong E,
Journal : Nature Genetics

Chromosome topology guides the Drosophila Dosage Compensation Complex for target gene activation

Author(s) : Schauer T, Ghavi-Helm Y, Sexton T, Albig C, Regnard C, Cavalli G, Furlong E, Becker P,
Journal : EMBO Rep

Dual functionality of cis-regulatory elements as developmental enhancers and Polycomb response elements.

Author(s) : Erceg J, Pakozdi T, Marco-Ferreres R, Ghavi-Helm Y, Girardot C, Bracken A, Furlong E,
Journal : Genes Dev

Corrigendum: Enhancer loops appear stable during development and are associated with paused polymerase.

Author(s) : Ghavi-Helm Y, Klein F, Pakozdi T, Ciglar L, Noordermeer D, Huber W, Furlong E,
Journal : Nature

Chromatin Immunoprecipitation for Analyzing Transcription Factor Binding and Histone Modifications in Drosophila.

Author(s) : Ghavi-Helm Y, Zhao B, Furlong E,
Journal : Methods Mol Biol

Identification and in silico modeling of enhancers reveals new features of the cardiac differentiation network.

Author(s) : Seyres D, Ghavi-Helm Y, Junion G, Taghli-Lamallem O, Guichard C, Roder L, Girardot C, Furlong E, Perrin L,
Journal : Development

FourCSeq: analysis of 4C sequencing data.

Author(s) : Klein F, Pakozdi T, Anders S, Ghavi-Helm Y, Furlong E, Huber W,
Journal : Bioinformatics

PHD and TFIIS-Like domains of the Bye1 transcription factor determine its multivalent genomic distribution.

Author(s) : Pinskaya M, Ghavi-Helm Y, Mariotte-Labarre S, Morillon A, Soutourina J, Werner M,
Journal : PLoS One

Enhancer loops appear stable during development and are associated with paused polymerase.

Author(s) : Ghavi-Helm Y, Klein F, Pakozdi T, Ciglar L, Noordermeer D, Huber W, Furlong E,
Journal : Nature

Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells.

Author(s) : Carriere L, Graziani S, Alibert O, Ghavi-Helm Y, Boussouar F, Humbertclaude H, Jounier S, Aude J, Keime C, Murvai J, Foglio M, Gut M, Gut I, Lathrop M, Soutourina J, Gerard M, Werner M,
Journal : Nucleic Acids Res

Analyzing transcription factor occupancy during embryo development using ChIP-seq.

Author(s) : Ghavi-Helm Y, Furlong E,
Journal : Methods Mol Biol

Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development.

Author(s) : Bonn S, Zinzen R, Girardot C, Gustafson E, Perez-Gonzalez A, Delhomme N, Ghavi-Helm Y, Wilczynski B, Riddell A, Furlong E,
Journal : Nat Genet

Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species.

Author(s) : Cazalet C, Jarraud S, Ghavi-Helm Y, Kunst F, Glaser P, Etienne J, Buchrieser C,
Journal : Genome Res

Genome-wide location analysis reveals a role of TFIIS in RNA polymerase III transcription.

Author(s) : Ghavi-Helm Y, Michaut M, Acker J, Aude J, Thuriaux P, Werner M, Soutourina J,
Journal : Genes Dev

Mediator-dependent recruitment of TFIIH modules in preinitiation complex.

Author(s) : Esnault C, Ghavi-Helm Y, Brun S, Soutourina J, Van Berkum N, Boschiero C, Holstege F, Werner M,
Journal : Mol Cell

Mutations of RNA polymerase II activate key genes of the nucleoside triphosphate biosynthetic pathways.

Author(s) : Kwapisz M, Wery M, Despres D, Ghavi-Helm Y, Soutourina J, Thuriaux P, Lacroute F,
Journal : EMBO J