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External seminar: Alain Chédotal
| When |
Jan 05, 2026
from 11:00 to 12:00 |
|---|---|
| Contact Name | Michalis Averof |
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External seminar: Alain Chédotal (Institut de la vision, Paris and MELIS, Lyon)
"Development and evolution of visual system connectivity”
Abstract:
In most vertebrates camera-style eyes contain retinal ganglion cell (RGC) neurons projecting to visual centers on both sides of the brain. However in fish RGCs are thought to only innervate the contralateral side. Using 3D imaging and tissue clearing we found that bilateral visual projections exist in non-teleost fishes. We also demonstrated that distinct developmental programs for visual system laterality between fishes and mammals. We are currently investigating human retinal development during the first trimester using transcriptomics and advanced 3D imaging techniques to map cell lineages and types. This work includes building a comprehensive 3D atlas of the developing oculomotor and eye vasculature systems, which will enhance our understanding of eye diseases and potentially improve replacement cell therapies.
Host: Michalis Averof
Monday, January 5th
Amphi L'huillier (physique)