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HDR defense: Julie Carnesecchi

When Oct 25, 2023
from 02:00 to 05:00
Where Salle des thèses
Contact Name
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Julie Carnesecchi will defend her Habilitation to supervise research on Wednesday, October 25 at 14:00 pm in the salle des thèses, on the topic of :

"Integrating transcription and mRNA processing networks into cell fate decision"


While the current view states that Transcription Factors (TFs) act on DNA regulatory elements to deploy precise gene programs, an emerging concept proposes that TFs also bind RNA and regulate mRNA biogenesis to promote molecular and cellular diversity. Yet, how the RNA regulatory functions of TFs contribute to their key role in cell fates remains puzzling. From in vitro interaction to tissue development, the HDR presentation will survey my previous work and our latest findings focusing on the splicing function and RNA-binding ability of the homeodomain TFs, using Drosophila muscle development as a paradigm of cell fate decisions.